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EPA and DHA status of South Asian and white Canadians living in the National Capital Region of Canada.

机译:居住在加拿大国家首都地区的南亚和白人加拿大人的EPA和DHA身份。

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To minimize the risk of cardiovascular disease (CVD), most dietary guidelines have recommended consuming 500 mg/day of eicosapentaenoic acid (EPA) + docosahexaenoic acid (DHA) or two servings of oily fish/week. The sum of percent EPA and DHA in red blood cell (RBC) total fatty acids-termed the omega-3 index-has been proposed as a biomarker for assessing the risk of death from CVD. The omega-3 indices of ≤4, >4 to <8 and ≥8 % have been proposed to be associated with high, intermediate and low CVD risks, respectively. In this study, we determined the EPA + DHA intake level and the omega-3 index of South Asian Canadians (SAC; n = 308) and white Canadians (WC; n = 341) age 20-79 years living in the National Capital Region of Canada. The mean EPA + DHA intake levels were 569 ± 571 mg/day for SAC and 684 ± 865 mg/day for WC and 46 % of SAC and 43 % of WC met the recommended EPA + DHA intake level of 500 mg/day. The mean omega-3 indices were 6.6 and 5.9 % for SAC and WC respectively. The suggested cardio-protective target level for the omega-3 index of ≥8 % was observed only in 19.8 % of SAC and in 9.4 % of WC subjects. The majority of the participants (74.4 % of SAC and 82.7 % of WC) were in the >4 to <8 % range. These results suggest that although study participants' dietary intake of EPA + DHA is adequate, this intake was not sufficient to provide an omega-3 index that is considered cardio-protective.
机译:为了最大程度地降低患心血管疾病(CVD)的风险,大多数饮食指南建议每周摄入500毫克/天的二十碳五烯酸(EPA)+二十二碳六烯酸(DHA)或两份油性鱼。已提出将红细胞(RBC)总脂肪酸中EPA和DHA的总和(称为omega-3指数)作为评估CVD死亡风险的生物标记。有人提出,omega-3指数≤4,> 4至<8和≥8%,分别与高,中和低CVD风险相关。在这项研究中,我们确定了居住在国家首都地区的年龄在20-79岁的南亚加拿大人(SAC; n = 308)和加拿大白人(WC; n = 341)的EPA + DHA摄入水平和omega-3指数。加拿大。 SAC的EPA + DHA平均摄入量为569±571 mg /天,WC和6%的SAC和43%的WC达到推荐的EPA + DHA摄入量500 mg /天为684±865 mg /天。 SAC和WC的平均omega-3指数分别为6.6%和5.9%。仅在19.8%的SAC和9.4%的WC受试者中观察到建议的omega-3指数的心脏保护目标水平≥8%。大多数参与者(SAC的74.4%和WC的82.7%)在> 4到<8%之间。这些结果表明,尽管研究参与者的饮食中EPA + DHA的饮食摄入量足够,但这种摄入量不足以提供被认为具有心脏保护作用的omega-3指数。

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