Highly selective determination of phenolphthalein by flow injectionchemiluminescence method based on a molecular imprinting polymer

摘要

ABSTRACT: The phenolphthalein-imprinted polymer was prepared with methacrylic acid as functional monomer and ethylene glycol dimethacrylate as cross-linker. Taking advantage of the quenching effect of phenolphthalein on the potassium permanganate– HCl–anhydrous alcohol chemiluminescence system, a new model was established to determine phenolphthalein by a highly selective flow injection chemiluminescence method. The traditional flow-though cell was replaced with a novel flow path using a Y-shaped polymethyl methacrylate column, through which the three reactants were injected simultaneously. The linear range of this assay was from 1.0 × 108 to 1.0 × 106 g/mL (r = 0.9978). The limit of detection was 8.9 × 109 g/mL. The relative standard deviation for the determination of 1.0 × 108 g/mL phenolphthalein solution was below 2.9% (n = 11). The proposed method was applied to the determination of phenolphthalein in real samples with satisfactory results.