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A Calcium Prerinse Required to Form Calcium Fluoride in Plaque from a Sodium Fluoride Rinse

机译:从氟化钠冲洗以在噬菌斑中形成氟化钙所需的钙预冲洗液

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摘要

The purpose of this study is to determine whether a calcium (Ca) prerinse used before a 228 μg/g (ppm) fluoride (F) rinse would induce the formation of 'calcium fluoride-like' (CaF2-like) deposits in human dental plaque. Sixty minutes after the use of the Ca prerinse/F rinse, plaque samples were collected from 10 volunteers, homogenized, and split into 2 aliquots. The plaque mass from one aliquot was then extracted with a 'plaque-like' solution that extracted all the CaF2-like deposits. The total F in both aliquots was then determined and compared. The results demonstrated that, as in previous studies, the Ca prerinse induced large increases in plaque fluid and total plaque F. However, unlike previous results without the Ca prerinse, 30% of the plaque F deposits were CaF2 or CaF2-like. Given that maintaining an elevated F concentration in the vicinity of a developing lesion may play an important role in the cariostatic effect of this ion, and the potential advantages of CaF2-like deposits as an F source, these results suggest that a Ca prerinse may increase the cariostatic effect of topical agents.
机译:这项研究的目的是确定在228μg/ g(ppm)氟化物(F)漂洗之前使用的钙(Ca)预漂洗是否会诱导人牙齿中形成“类氟化钙”(CaF2)沉积物牌匾。在使用Ca预漂洗/ F漂洗后60分钟,从10名志愿者中收集了噬菌斑样品,进行了均质化处理,并分成2等份。然后用“噬斑样”溶液从一个等分试样中提取噬斑块,该溶液提取了所有的CaF2样沉积物。然后确定并比较两个等分试样中的总F。结果表明,与以前的研究一样,Ca预酶引起的斑块液和总斑块F大大增加。但是,与先前没有Ca预酶的结果不同,30%的斑块F沉积物为CaF2或CaF2样。鉴于在发展中的病变附近维持较高的F浓度可能在该离子的抗癌作用中起着重要作用,并且类似CaF2的沉积物作为F源的潜在优势,这些结果表明Ca预漂洗液可能会增加外用药物的抗癌作用。

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