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首页> 外文期刊>Lab on a chip >Foil assisted replica molding for fabrication of microfluidic devices and their application in vitro
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Foil assisted replica molding for fabrication of microfluidic devices and their application in vitro

机译:用于微流体装置制造的箔辅助复制品成型及其在体外的应用

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We present a simple, rapid, benchtop. Foil Assisted Rapid Molding (FARM) method for the fabrication of microfluidic devices. This novel technique involves the use of aluminium foil, pen and an X-Y plotter to create semi-circular or plano-concave, shallow microchannels. It is an easy do-it-yourself (DIY) technique for creating a microfluidic device in three simple steps: (1) create a channel design using the CAD software, (2) plot the patterns on aluminium foil and (3) use the reverse of the engraved foil as a mold to create microfluidic devices. In this report, we present a detailed study of the proposed method by varying a range of parameters such as foil thickness, tip material, and tip sizes and by investigating their effect on the creation of channels with varying geometry. Furthermore, we demonstrated the cytocompatibility of these devices in vitro.
机译:我们提出了一个简单,快速的台式机。铝箔辅助快速成型(FARM)方法用于制造微流控设备。这项新技术涉及使用铝箔,钢笔和X-Y绘图仪来创建半圆形或平凹的浅微通道。这是一种简单的自行完成(DIY)技术,可通过三个简单步骤来创建微流体设备:(1)使用CAD软件创建通道设计,(2)在铝箔上绘制图案,(3)使用将雕刻的箔片作为模型反向制作微流控设备。在此报告中,我们通过改变一系列参数(例如箔厚度,刀头材料和刀头尺寸)并研究其对创建具有不同几何形状的通道的影响,对提出的方法进行了详细研究。此外,我们证明了这些设备在体外的细胞相容性。

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