Response to Protocol Review Scenario: Too many problems.

摘要

The Animal Welfare Act makes it clear that multiple surgical procedures included within one protocol must be justified for scientific reasons and preapproved by the IACUC We feel that Wycoff has not adequately justified the scientific reasons. His argument about subjecting fewer animals to more pain is not scientific. Wycoff also proposed only "adequate" pain control. The definition of adequate is open to interpretation but may imply that there is room for improvement. One way that Wycoff could convince the IACUC that he is concerned about pain control would be to use a pain scoring sheet detailing the frequency of monitoring and any plans to increase administration of pain-relieving medications if indications of pain or discomfort are observed.