Synthese organique sous mlcro-ondes en absence de solvant

摘要

Solvent-free methods are especially adapted to organic synthesis under green chemistry conditions.When coupled to microwave(MW)irradiation,it results very efficient and clean procedures with noticeable improvements over classical methods.To take advantage of MW specific effects,the most suitable cases involve reactions with polar mechanisms with increases of the polarity during the progress of the reaction and late transition states along the reaction coordinates.Striking examples are described therein highlighting the noticeable potentialities in theses techniques.