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首页> 外文期刊>Lancet Neurology >Dysphagia in acute stroke: a long-awaited trial.
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Dysphagia in acute stroke: a long-awaited trial.

机译:急性中风的吞咽困难:期待已久的试验。

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Carnaby and colleagues1 describe in this issue of The Lancet Neurology the results of their single centre, sing le-blind, randomised controlled trial of a standard behavioural intervention for dysphagia after stroke as "encouraging". I might even add the adjective exciting, because this trial has shown, for the first time, that an intervention can improve outcomes of patients with dysphagia. Dysphagia is more common in severe stroke, but is independently associated with poorer long-term outcomes in mild-to-moderate stroke. This trial indicates that a behavioural intervention not only improves recovery of swallowing, but also reduces the complications of dysphagia and improves long-term outcomes. This finding lends support to the notion that the association between dysphagia and poor outcomes is, at least in part, causal. Because almost half of all patients admitted to hospital with an acute stroke worldwide have dysphagia an effective treatment would be applicable to millions of patients each year, andtherefore might have huge public-health benefits. However, before we get overly excited we must consider the limitations of this study, some of which the authors describe in their discussion.
机译:Carnaby及其同事1在本期《柳叶刀神经病学》(The Lancet Neurology)中描述了他们的单中心研究结果,该研究以“令人鼓舞”的方式对中风后吞咽困难的标准行为干预进行了乐盲,随机对照试验。我什至可以添加令人兴奋的形容词,因为该试验首次显示干预可以改善吞咽困难患者的预后。吞咽困难在重度中风中更为常见,但与轻度至中度中风的长期预后不良无关。该试验表明,行为干预不仅可以改善吞咽的恢复,还可以减少吞咽困难的并发症并改善长期预后。这一发现为吞咽困难和不良预后之间的联系至少部分是因果关系这一观点提供了支持。由于全世界因急性中风入院的患者中几乎有一半患有吞咽困难,因此每年有数百万患者可以接受有效治疗,因此可能具有巨大的公共卫生益处。但是,在我们变得过于兴奋之前,我们必须考虑这项研究的局限性,其中一些在作者的讨论中进行了描述。

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