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首页> 外文期刊>Nutrition, metabolism, and cardiovascular diseases: NMCD >Association between maternal serum high mobility group box 1 levels and pregnancy complicated by gestational diabetes mellitus
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Association between maternal serum high mobility group box 1 levels and pregnancy complicated by gestational diabetes mellitus

机译:孕妇血清高迁移率族第1框水平与妊娠合并妊娠糖尿病的关系

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摘要

Background and aims: Gestational diabetes mellitus (GDM), is characterized by chronic, low-grade subclinical inflammation with altered production of cytokines and mediators. Recently, a new protein acting as a "danger signal", high mobility group box 1 (HMGB1), that migrates quickly during electrophoresis, has been identified. The aim of our study was to analyze serum levels of HMGB1 in pregnant women, with or without GDM, in the third trimester of pregnancy to evaluate correlation with insulin resistance and other risk factors for GDM.
机译:背景与目的:妊娠期糖尿病(GDM)的特征是慢性,低度亚临床炎症,其细胞因子和介体的产生发生变化。最近,已经鉴定出一种新的蛋白质,它是“危险信号”,高迁移率族盒1(HMGB1),在电泳过程中会快速迁移。我们研究的目的是分析妊娠晚期三个月有或没有GDM的孕妇血清HMGB1的水平,以评估与胰岛素抵抗和其他GDM危险因素的相关性。

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