Heparin-induced thrombocytopenia without thrombocytopenia in an intensive care unit Thrombopenie induite par I'heparine sans thrombopenie vraie dans une reanimation

摘要

Heparin-induced thrombocytopenia (HIT) is a side effect of heparin therapy, mediated by PF4 antibodies to heparin. It is associated with the risk of multiple arterial and venous thromboses, and a high morbidity and mortality. Indeed, the lack of recognition of HIT and the lack or the delay in treatment interruption can lead to serious consequences [1]. A 56-year-old man was admitted to our intensive care unit on January 4, 2011, for complete left hemiplegia and impaired consciousness. A CT scan of his brain showed a right capsulo-lenticular hemorrhagic stroke, with some blood in the right lateral ventricle, causing a midline shift. He was receiving aspirin for peripheral arterial disease and was treated for severe hypertension. Excessive consumption of alcohol was noted, as well as active smoking.