7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

Seela F; Peng X; Ming X

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7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

机译：7-脱氮嘌呤-2,6-二胺和7-脱氮鸟嘌呤：7-取代核苷和寡核苷酸的合成和性质。

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摘要

The synthesis of 7-substituted 7-deazaguanine and 7-deazaadenine ribonucleosides 1-2, the incorporation of 3a-d into oligonucleotides, and the stability of the corresponding duplexes and base discrimination are described. The pKa values of 3-4 are determined.

机译：描述了7-取代的7-脱氮鸟嘌呤和7-脱氮氮腺嘌呤核糖核苷1-2的合成，将3a-d掺入寡核苷酸，以及相应双链体的稳定性和碱基区分。确定pKa值为3-4。

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《Nucleosides, nucleotides and nucleic acids》 |2005年第7期|共3页
作者
Seela F; Peng X; Ming X;
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正文语种 eng
中图分类基础医学;
关键词
Diamines; Guanine; Nucleosides; Oligonucleotides; Purine Nucleosides; 二胺类; 鸟嘌呤; 核苷类; 寡核苷酸类; 嘌呤核苷类;

机译：Diamines;Guanine;Nucleosides;Oligonucleotides;Purine Nucleosides;二胺类;鸟嘌呤;核苷类;寡核苷酸类;嘌呤核苷类;

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1. 7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides. [J] . Seela F, Peng X, Ming X Nucleosides, nucleotides and nucleic acids . 2005,第5a7期

机译：7-脱氮嘌呤-2,6-二胺和7-脱氮鸟嘌呤：7-取代核苷和寡核苷酸的合成和性质。
2. 7-substituted 8-aza-7-deazapurines and 2,8-diaza-7-deaza-purines: synthesis of nucleosides and oligonucleotides. [J] . Lin W, Xu K, Seela F Nucleosides, nucleotides and nucleic acids . 2005,第5a7期

机译：7-取代的8-氮杂7-脱氮嘌呤和2,8-二氮杂7-脱氮嘌呤：核苷和寡核苷酸的合成。
3. 8-aza-7-deazaadenine and 7-deazaguanine: synthesis and properties of nucleosides and oligonucleotides with nucleobases linked at position-8. [J] . Seela F, Debelak H Nucleosides, nucleotides and nucleic acids . 2001,第4a7期

机译：8-aza-7-deazaadenine和7-deazaguanine：核苷和寡核苷酸的合成和性质（在8位连接有核碱基）。
4. A STRUCTURAL ISOMER OF CL-20: SYNTHESIS, CHARACTERIZATION AND ENERGETIC PROPERTIES OF N~3,N~6-BIS(2,2,2-TRINITROTETHYL)-1,2,4,5-TETRAZINE-3,6-DIAMINE [C] . Michael Goebell, Thomas M. Klapoetke Seminar on new trends in research of energetic materials;NTREM '09 . 2009

机译：CL-20的结构异构体：N〜3，N〜6-BIS（2,2,2-三亚丁基）-1,2,4,5-四嗪-3,6-二胺的合成，表征和能量性质
5. Chemistry for gene silencing: 4'-modified and 2'-fluorinated nucleosides and oligonucleotides. [D] . Watts, Jonathan K. 2008

机译：基因沉默化学：4'-修饰的和2'-氟化的核苷和寡核苷酸。
6. Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides. [O] . R T Pon, M J Damha, K K Ogilvie 1985

机译：在寡核苷酸的固相合成过程中通过核苷亚磷酰胺试剂修饰鸟嘌呤碱基。
7. Modification of guanine bases by nucleoside phosphoramidite reagents during the solid phase synthesis of oligonucleotides. [O] . Pon, R T, Damha, M J, Ogilvie, K K 1985

机译：在寡核苷酸的固相合成过程中通过核苷亚磷酰胺试剂修饰鸟嘌呤碱基。

7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides.

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