In the era of preventive medicine, disease screening has both gained momentum and invoked controversy. Rational screening requires sophisticated knowledge in the areas of genetic predisposition and environmental risk factors as well as the interaction between these 2 factors. Knowledge in these areas vis-a-vis intracranial aneurysms (IAs) remains too primitive to justify routine screening. Nonetheless, recent genomewide association studies have shed light on specific single nucleotide polymorphisms (SNPs) associated with an increased risk of IA development.
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