Asymmetric organocatalytic Michael addition of azlactones to cis-1,2-bis(phenylsulfbnyl)ethene. A simple entry to quaternary α-amino acids

摘要

Azlactones react with 1,2-bis(phenylsulfonyl)ethene under catalysis by simple chiral thioureas, affording α,α-disubstituted α-amino acid derivatives in good yields and in moderate to good enantioselectivities.