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Intraparenchymal Posterior Circulation Cerebral Aneurysm: A Case Report

机译:实质内后循环脑动脉瘤:一例报告

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ABSTRACT Cerebral arterial aneurysms are a significant source of morbidity and mortality throughout the world. Cerebral aneurysms are well documented, with characteristic imaging findings both pre- and postrupture and typical morphologies and locations well described in the literature. Our case illustrates a rare entity of an intraparenchymal cerebral arterial aneurysm; an entity which was previously described rarely and only within the anterior circulation. We present a very rare case of an incidentally discovered, partially thrombosed posterior circulation (PICA) aneurysm fully invested within the parenchyma of the medulla. A 41-year-old man with no known past medical history presented as an unrestrained passenger status post-motor vehicle collision, seated in the rear of a prisoner transport van near the point of impact. On presentation he was alert and oriented, with a reported Glasgow Coma Scale of 15. The patient was able to provide history and reported loss of consciousness initially after the collision and, on presentation to the emergency department, complained of headache and "blurry vision." A CT scan of the brain was ordered by the emergency physician. Noncontrast-enhanced CT scan of the brain demonstrated a focus of hyper-attenuation in the region of the obex, on the inferior most sections. No other focal abnormalities were identified. Given the history of trauma, the differential diagnosis included a brain stem or fourth ventricle hemorrhage versus an incidental mass lesion, such as a cavernous malformation, hemangioblastoma, or possibly meningi-oma. A neurosurgery consult was obtained and the patient, who remained clinically stable, went on to MR imaging of the brain. On MR imaging, the lesion was noted to be well circumscribed, with a smooth semilunar hemosiderin rim and central T1 hyperintensity, and was fully invested within the parenchyma of the medulla (Fig 1). Given the hemosiderin rim and intrinsic T1 hyper intensity representing various stages of blood products, cavernous malformation remained a differential diagnostic consideration (Fig 2).1 There was minimal mass effect, making other mass lesions much less likely. However, despite the signal intensity characteristics, which were typical of cavernous malformation, the smooth nature of the rim versus the classic "popcorn" appearance expected in cavernous malformation led to continued inclusion of atypical aneurysm on the differential. CTA and then conventional angiogram were subsequently performed and confirmed the diagnosis of PICA branch aneurysm (Figs. 3 and 4). The various stages of blood products seen on MR imaging suggested prior partial thrombosis. The patient was treated with dexamethasone, aspirin, and plavix before undergoing endovascular stent placement and coiling. He complained of intermittent diplopia immediately postprocedure, which corresponded with a right homonymous hemianopsia on neuro-opthalmologic testing. His symptoms gradually decreased in frequency before discharge.
机译:摘要脑动脉瘤是全世界发病率和死亡率的重要来源。充分记录了脑动脉瘤,破裂前和破裂后的特征性影像学表现以及典型的形态和位置均在文献中有很好的描述。我们的病例说明了实质性脑实质内动脉瘤的罕见情况。先前很少描述且仅在前循环内的实体。我们提出了一个非常罕见的案例,即偶然发现了完全投资于延髓实质内的部分血栓性后循环(PICA)动脉瘤。一名41岁的男子,在撞车事故发生后坐在囚车的后方,在撞车后处于不受约束的乘客状态,他的既往病史不明。出诊时,他机敏而定向,据报道格拉斯哥昏迷评分为15。患者在碰撞后最初能够提供病史并报告失去知觉,而在向急诊科就诊时,则抱怨头痛和“视力模糊”。 ”急诊医师下令对大脑进行CT扫描。对脑部进行非对比增强的CT扫描显示,在大部分下半部的小便区域中,过度衰减是一个重点。没有发现其他局灶性异常。考虑到外伤史,鉴别诊断包括脑干或第四脑室出血与偶发的肿块,如海绵状畸形,成血管细胞瘤或可能的脑膜瘤。获得了神经外科咨询,并且该患者在临床上保持稳定,随后继续进行了脑部MR成像。在MR成像上,病灶已被很好地界定,具有光滑的半月型铁血黄素铁环边缘和中央T1高强度,并已充分投资于髓质实质内(图1)。考虑到铁血黄素的边缘和内在的T1高强度代表了血液制品的各个阶段,海绵状畸形仍然是鉴别诊断的考虑因素(图2)。1肿块效应最小,其他肿块病变的可能性很小。然而,尽管信号强度特征是海绵状畸形的典型特征,但轮缘的平滑性质与海绵状畸形中预期的经典“爆米花”外观相比却导致了持续性的非典型动脉瘤持续出现在鉴别上。随后进行了CTA检查,然后进行了常规血管造影,并证实了PICA分支动脉瘤的诊断(图3和4)。在MR成像上看到的血液制品的各个阶段提示了先前的部分血栓形成。在进行血管内支架置入和卷绕之前,该患者接受了地塞米松,阿司匹林和普拉维治疗。他抱怨在手术后立即出现间歇性复视,这与神经眼科检查中的右同名半盲症相对应。出院前,他的症状逐渐减少。

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