A Supranuclear Disorder of Ocular Motility as a Rare Initial Presentation of Motor Neurone Disease

摘要

A case is described of motor neurone disease presenting with an ocular motor disorder characterised by saccadic intrusions, impaired horizontal and vertical saccades, and apraxia of eyelid opening. The occurrence of eye movement abnormalities in motor neurone disease is discussed. A 71-year-old man presented with difficulty opening and moving his eyes. He described a feeling as if his 'eyes were locked straight ahead'. His visual acuity was 6/9 bilaterally. He had apraxia of lid opening, saccadic intrusions, and difficulty generating horizontal and vertical saccades. However, oculocephalic testing revealed a full range of movement.