Preparation of 2,7-diaminofluorenone derivatives by palladium catalyzed amination

摘要

A convenient synthesis of tert-2,7-diaminofluorenonens 3a-3e via palladium catalyzed reaction of secondary amines with 2,7-dibromofluorene and subsequent oxidation is described. In the cases were non-cyclic secondary amines are applied, the aniline derivatives 4c-4e are formed as side products by a dehydrohalogenation reaction. [References: 21]