An Efficient Route to Phenylselenoethers in the Presence of Ag20

摘要

An efficient protocol for the preparation of phenylselenoethers from unsaturated alcohols using phenylse-lenenyl halides at room temperature was developed. The procedure employs phenylselenenyl chloride and bromide, some DELTA~4 - and DELTA~5 -alkenols and Ag2O, as an additive, to generate the tetrahydropyrans or tetrahydrofurans. This method permits the preparation of cyclic phenylselenoethers in high yields and under extremely mild conditions.