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Tumour microenvironment: More than just a mutagen

机译:肿瘤微环境:不仅仅是诱变剂

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Background: A previously described economic model was based on average values for patients diagnosed with chronic periodontitis (CP). However, tooth loss varies among treated patients and factors for tooth loss include CP severity and risk. The model was refined to incorporate CP severity and risk to determine the cost of treating a specific level of CP severity and risk that is associated with the benefit of tooth preservation. Methods: A population that received and another that did not receive periodontal treatment were used to determine treatment costs and tooth loss. The number of teeth preserved was the difference of the number of teeth lost between the two populations. The cost of periodontal treatment was divided by the number of teeth preserved for combinations of CP severity and risk. Results: The cost of periodontal treatment divided by the number of teeth preserved ranged from (US) 1,405 to 4,895 for high or moderate risk combined with any severity of CP and was more than 8,639 for low risk combined with mild CP. The cost of a three-unit bridge was 3,416, and the cost of a single-tooth replacement was 4,787. Conclusion: Periodontal treatment could be justified on the sole basis of tooth preservation when CP risk is moderate or high regardless of disease severity.
机译:背景:先前描述的经济模型基于诊断为慢性牙周炎(CP)的患者的平均值。但是,牙齿脱落在接受治疗的患者中有所不同,并且牙齿脱落的因素包括CP的严重程度和风险。对模型进行了完善,以纳入CP严重性和风险,以确定治疗特定水平的CP严重性和风险的成本,该成本与牙齿保护的益处相关。方法:采用接受牙周治疗的人群和未接受牙周治疗的人群来确定治疗费用和牙齿脱落。保存的牙齿数量是两个种群之间丢失的牙齿数量之差。牙周治疗的费用除以因CP严重性和风险而保留的牙齿数量。结果:牙周病治疗费用除以保存的牙齿数量范围从(美国)1,405至4,895(高或中度风险,伴有任何CP严重程度),而低风险,超过轻度CP(伴有轻度CP)则超过8,639。三单元桥的成本为3,416,单齿更换的成本为4,787。结论:无论疾病的严重程度如何,CP风险为中度或高度时,仅凭牙齿保护就可以进行牙周治疗。

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