Direct immoblization of DNA on diamond-like carbon nanodts

摘要

We report an alternative technique for the immobilization of biological species in the sub-100 nm range. The feasibility of attaching DNA to electron-beam-deposited diamond-like carbon nanodots has been demonstrated. The key point of this approach is that direct patterning of a glass substrate is combined with a resist-free technique. Compared with conventional writing approaches, the high-resolution method presented here is simple, flexible, and compatible with the manipulation of a wide range of biological species.