Mesoporous Silica Particles as Nanocontainers for Phthalocyanine Photosensitizers: Estimation of Efficiency in In Vivo Experiments

摘要

The template synthesis of mesoporous silica nanoparticles with predetermined size and porous structure is carried out. Water-soluble photosensitizer Photosens is used to study the possibility of applying such particles as containers for photosensitizers of a phthalocyanine series. In vivo experiments have shown that the application of such nanocontainers for the delivery of Photosens to a tumor makes it possible to improve the efficiency of fluorescence diagnostics and the photodynamic therapy of cancer.