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BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2

机译:GREM1和GREM2以基因特异性方式调节人胎儿卵巢体细胞中的BMP信号传导

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摘要

Do changes in the expression of bone morphogenetic proteins (BMPs) 2 and 4, and their antagonists Gremlin1 (GREM1) and Gremlin2 (GREM2) during human fetal ovarian development impact on BMP pathway activity and lead to changes in gene expression that may influence the fate and/or function of ovarian somatic cells?
机译:在人类胎儿卵巢发育过程中,骨形态发生蛋白(BMPs)2和4及其拮抗剂Gremlin1(GREM1)和Gremlin2(GREM2)的表达是否发生变化,从而影响BMP途径的活性并导致可能影响命运的基因表达变化和/或卵巢体细胞的功能?

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