Synthesis and Study of Sorption Properties of Molecularly Imprinted Polymers for Quercetin

摘要

Molecularly imprinted polymers for quercetin and the corresponding nonimprinted blank polymers (control polymers) have been synthesized using acrylamide and 2-(dimethylamino)-ethylmethacrylate as functional monomers. It has been shown that the nature of the template, the ratio of the functional monomer to template within the prepolymerization mixture, and the amount of crosslinker, which were varied at the synthesis stage, influenced on the sorption properties of molecularly imprinted polymers for quercetin. Synthesis conditions were optimized by varying the composition of the prepolymerization mixture. The sorption properties of the obtained materials have been studied. The estimation of selectivity of a sorbent with the imprints of quercetin was carried out by the example of structurally related compounds. It has been shown that the acrylamide-based polymer was able to selectively sorb quercetin, the binding sites of the quercetin being mainly of hydrophobic structure.