The role of para-meta isomerization in the selective synthesis of para-tert-butylphenol in the presence of modern macroporous sulfonic cation-exchange resins

摘要

The formation of meta-tert-butylphenol (m-TBP), which decreasing the quality of the commercial product, is shown to be possible in the target synthesis of para-tert-butylphenol (p-TBP) in the presence of sulfonic cation-exchange resins using macroporous Amberlyst 36 Dry as an example. The equilibrium concentration of m-TBP in the liquid phase (the maximum value at 409 K is 47 wt %) is calculated from experimental and published data. Up to 10 wt % m-TBP (on the reaction mixture basis) is formed at the maximum values of temperature (409 K) and contact time (450 min). Kinetic characteristics are determined for the + phenol reaction, which supplements the kinetic model for the production of p-TBP. The rate constants of this reaction are several orders of magnitude smaller than those for the main (ortho-para) transformations. The temperature range (353-383 K) and contact time at which the formation of m-TBP is minimum and exerts no effect on the qualitative characteristics of the target p-isomer are determined.