Cellulose acetate microparticles for Lab-on-a-chip applications

摘要

Lab-on-a-chip technology represents a revolution in lab-oratory experimentation and permits testing to move from the central laboratory into micro-devices made of different materials (glass, silicon, polymers). The main advantages of the new devices are integration of multiple steps in complex analytical procedures, diversity of application, sub-microliter consumption of reagents and sample, and portability. In order to propose a microparticle formulation specially designed for lab-on-a-chip application, cellulose acetate (CA) were considered. Since size and morphology of microparticles are expected to reasonably influence the microparticles performances, the investigated by optical and scanning electron microscopy optical sizer. Different types of dyes were used to increase microparticle visibility in the devices.