...
首页> 外文期刊>Medicine. >Short-stem prostheses in primary total hip arthroplasty: A meta-analysis of randomized controlled trials
【24h】

Short-stem prostheses in primary total hip arthroplasty: A meta-analysis of randomized controlled trials

机译:初次全髋关节置换术中的短柄假体:一项随机对照试验的荟萃分析

获取原文
获取原文并翻译 | 示例
   

获取外文期刊封面封底 >>

       

摘要

Background:Short-stem (SS) prostheses require less resection of the femoral neck, produce a more physiological load pattern in the proximal femur, reduce stress shielding, and aid bone conservation and are, therefore, beneficial for young patients. Conventional cementless implants in total hip arthroplasty (THA) have shown excellent clinical results; however, it is unclear whether SS prostheses can obtain the same clinical and radiological outcomes. We conducted a meta-analysis of randomized controlled trials (RCTs) to evaluate whether SS prostheses are superior to conventional implants after primary THA.Methods:We reviewed the literature published up to June 2016 from PubMed, Web of Science, and the Cochrane Library to find relevant RCTs comparing SSs and conventional stems in primary THA. Quality assessment was performed by 2 independent reviewers. The RevMan 5.3 software program of the Cochrane Collaboration was used to analyze the data. Random- or fixed-effect models were used to calculate standardized mean differences (SMDs) and 95% confidence intervals (CIs) for each comparison.Results:Six RCTs involving 552 patients with 572 hips were identified. Strong evidence indicated that SS prostheses were more effective for reducing thigh pain than conventional implants (I-2 = 46%, P = 0.002; risk ratio [RR], 95% CI 0.15, 0.04-0.49). However, there were no significant differences between the 2 groups in Harris Hip Scores (I-2 = 0%, P = 0.84; SMD, 95% CI 0.02, -0.15-0.18), Western Ontario and McMaster Universities Osteoarthritis Index Scores (I-2 = 0%, P = 0.35; SMD, 95% CI 0.09, -0.10-0.27), femoral offset of stem (I-2 = 0%, P = 0.57; SMD, 95% CI 0.06, -0.16-0.29), and leg-length discrepancy (I-2 = 79%, P = 0.88; SMD, 95% CI 0.04, -0.44-0.51).Conclusion:SS prostheses achieve the same clinical and radiological outcomes as conventional implants, and were superior in terms of reducing thigh pain. But whether the postoperative thigh pain applied in 2nd-generation cementless prosthesis still needs further large-scale multicenter studies with longer follow-up to confirm.
机译:背景:短柄(SS)假体需要较少的股骨颈切除,在股骨近端产生更多的生理负荷模式,减少应力屏蔽,并有助于骨骼保护,因此对年轻患者有益。全髋关节置换术(THA)中的常规非骨水泥植入物已显示出出色的临床效果;然而,尚不清楚SS假体能否获得相同的临床和放射学结果。我们进行了一项随机对照试验(RCT)的荟萃分析,以评估原发性THA后SS假体是否优于常规植入物。方法:我们审查了PubMed,Web of Science和Cochrane Library截至2016年6月的文献。找到比较原发性THA中SS和常规茎的RCT。由2位独立审阅者进行质量评估。使用Cochrane协作公司的RevMan 5.3软件程序来分析数据。每次比较均使用随机或固定效应模型计算标准化均值差(SMD)和95%置信区间(CIs)。结果:确定了涉及552例572髋患者的6个RCT。有力的证据表明,SS假肢比常规假肢更有效地减轻大腿疼痛(I-2 = 46%,P = 0.002;风险比[RR],95%CI 0.15,0.04-0.49)。但是,两组的哈里斯髋关节评分(I-2 = 0%,P = 0.84; SMD,95%CI 0.02,-0.15-0.18),西安大略省和麦克马斯特大学骨关节炎指数评分(I -2 = 0%,P = 0.35; SMD,95%CI 0.09,-0.10-0.27),股骨干偏移(I-2 = 0%,P = 0.57; SMD,95%CI 0.06,-0.16-0.29 )和腿长差异(I-2 = 79%,P = 0.88; SMD,95%CI 0.04,-0.44-0.51)。结论:SS假体的临床和放射学结果与常规植入物相同,并且效果更好在减轻大腿疼痛方面。但是,是否在第二代非骨水泥假体中使用术后大腿疼痛仍需要进一步的大规模多中心研究,并需要更长的随访时间才能确定。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号