Adult-Onset Still Disease Manifestations, Treatment, Outcome, and Prognostic Factors in 57 Patients

Gerfaud-Valentin Mathieu; Maucort-Boulch Delphine; Hot Arnaud; Iwaz Jean; Ninet Jacques; Durieu Isabelle; Broussolle Christiane; Seve Pascal

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Adult-Onset Still Disease Manifestations, Treatment, Outcome, and Prognostic Factors in 57 Patients

机译：57例成人发作静止疾病的表现，治疗，结果和预后因素

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摘要

We conducted a retrospective observational study to describe a cohort and identify the prognostic factors in adult-onset Still disease (AOSD). Patients enrolled in this retrospective chart review fulfilled either Yamaguchi or Fautrel criteria. Candidate variables were analyzed with logistic unadjusted and adjusted regression models.

机译：我们进行了一项回顾性观察性研究，以描述一个队列并确定成人发作性斯蒂尔疾病（AOSD）的预后因素。参加此回顾性图表审查的患者符合Yamaguchi或Fautrel标准。候选变量使用逻辑未调整和调整后的回归模型进行分析。

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《Medicine.》 |2014年第2期|共9页
作者
Gerfaud-Valentin Mathieu; Maucort-Boulch Delphine; Hot Arnaud; Iwaz Jean; Ninet Jacques; Durieu Isabelle; Broussolle Christiane; Seve Pascal;
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正文语种 eng
中图分类医药、卫生;
关键词
RHS = reactive hemophagocytic syndrome; ESR = erythrocyte sedimentation rate; RA = receptor antagonist; CSs = corticosteroids; CRP = C-reactive protein; AOSD = adult-onset Still disease; CI = confidence interval; TNF-alpha = tumor necrosis factor alpha; CT = computed tomography; DMARDs = disease-modifying antirheumatic drugs; BM = bone marrow; 18FDG-PET = 18F-fluorodeoxyglucose positron emission tomography; GF = glycosylated ferritin; AE = adverse event; IVIg = polyvalent intravenous immunoglobulins; PMN = polymorphonuclear neutrophils; SF = serum ferritin; OR = odds ratio; MTX = methotrexate; IL = interleukin; SD = standard deviation; NSAIDs = nonsteroidal antiinflammatory drugs;

机译：RHS =反应性噬血细胞综合征;ESR =红细胞沉降率;RA =受体拮抗剂;CSs =皮质类固醇;CRP = C反应蛋白;AOSD =成年发作性静止疾病;CI =置信区间;TNF-alpha =肿瘤坏死因子α;CT =计算机断层扫描;DMARDs =改善疾病的抗风湿药;BM =骨髓;18FDG-PET = 18F-氟脱氧葡萄糖正电子发射断层扫描;GF =糖基化铁蛋白;AE =不良事件;IVIg =多价静脉内免疫球蛋白;PMN =多形核中性白细胞;SF =血清铁蛋白;OR =比值比;MTX =甲氨蝶呤;IL =白介素;SD =标准差;NSAIDs =非甾体抗炎药;

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Adult-Onset Still Disease Manifestations, Treatment, Outcome, and Prognostic Factors in 57 Patients

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