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首页> 外文期刊>Medical Physics >EPID dosimetry: effect of different layers of materials on absorbed dose response.
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EPID dosimetry: effect of different layers of materials on absorbed dose response.

机译:EPID剂量测定:不同材料层对吸收剂量反应的影响。

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摘要

PURPOSE: Commercial EPIDs are normally used in indirect detection mode (iEPID) where incident x-ray photons are converted to optical photons in a phosphor scintillator, which are then detected by a photodiode array. The EPIDs are constructed from a number of nonwater equivalent materials which affect the dose response of the detector. The so-called direct detection EPIDs (dEPIDs), operating without the phosphor layer, have been reported to display dose response close to in-water data. In this study, the effect that different layers of materials in the EPID have on the dose response was experimentally investigated and evaluated with respect to changes in field size response and beam profiles. METHODS: An iEPID was disassembled and the different layers of materials were removed or replaced with other materials. Data were also obtained on and off the support arm and with a sheet of opaque paper blocking the optical photons from the gadolinium oxysulfide (Gd2S2O:Tb) phosphor layer. Field size response was measured for field sizes ranging from 2 x 2 to 25 x 25 cm2, and profiles for the 25 x 25 cm2 beams were extracted from the data. RESULTS: The iEPID configuration was found to be very sensitive to backscatter. The increases in output with solid water backscatter compared to the no backscatter case were 14.7% and 6.6% at the largest field size investigated for the 6 and 18 MV beams, respectively. The Gd2S2O:Tb phosphor layer had a large influence on field size response as well as beam profiles for 6 MV photons, while no major effects were observed for the 18 MV beam. For 18 MV large differences in dose response were found when the standard 1 mm Cu buildup was changed for dmax equivalent Cu or solid water buildup, indicating that head scatter largely influences dose response for this energy. When the optical photons originating in the Gd2S2O:Tb layer were blocked from reaching the photodiodes, both field size output data and beam profiles corresponded well with data obtained in the dEPID configuration as well as reference ion chamber data for both energies. CONCLUSIONS: As expected, changing the layers of material in the EPID had a dramatic effect on dose response, which was often quite complex. For 6 MV, the complex dose response is mainly caused by the optical photons from the Gd2S2O:Tb layer, while insufficient filtering of scattered radiation largely affects the dose response for the 18 MV beam. The iEPID was also found to be very sensitive to backscatter for both energies. Blocking the optical photons created in the Gd2S2O:Tb layer essentially changed the iEPID configuration into the dEPID configuration, thus demonstrating great potential for a system that can be optimized for both imaging and dosimetry.
机译:用途:商业EPID通常用于间接检测模式(iEPID),在这种模式下,入射的X射线光子在磷光闪烁体中转换为光学光子,然后由光电二极管阵列进行检测。 EPID由许多非水等效材料构成,这些材料会影响检测器的剂量响应。据报道,在没有荧光粉层的情况下运行的所谓直接检测EPID(dEPID)显示的剂量响应接近于水中数据。在这项研究中,通过实验研究和评估了EPID中不同材料层对剂量响应的影响,并针对了场尺寸响应和光束分布的变化进行了评估。方法:拆解一个iEPID,然后移除不同层的材料或将其替换为其他材料。还获得了在支撑臂上和下的数据,并用一张不透明的纸阻挡了来自氧硫化(Gd2S2O:Tb)荧光粉层的光学光子。测量了2 x 2至25 x 25 cm2范围内的场大小响应,并从数据中提取了25 x 25 cm2光束的轮廓。结果:发现iEPID配置对反向散射非常敏感。与无背向散射情况相比,在没有最大背向散射情况下,固体水向后散射的输出增加分别为14.7%和6.6%,这是针对6 MV和18 MV光束进行的。 Gd2S2O:Tb荧光粉层对6 MV光子的场尺寸响应以及光束轮廓有很大影响,而对于18 MV光束则没有观察到主要影响。对于18 MV,当将标准1 mm Cu堆积更改为dmax等效Cu或固体水堆积时,发现剂量响应存在很大差异,这表明压头散射很大程度上影响了该能量的剂量响应。当阻止源自Gd2S2O:Tb层的光子到达光电二极管时,场大小输出数据和束轮廓都与dEPID配置中获得的数据以及两种能量的参考离子室数据都很好地对应。结论:正如预期的那样,更改EPID中的材料层对剂量响应具有显着影响,而剂量响应通常非常复杂。对于6 MV,复杂的剂量响应主要是由来自Gd2S2O:Tb层的光学光子引起的,而对散射辐射的过滤不充分会大大影响18 MV光束的剂量响应。还发现iEPID对两种能量的反向散射都非常敏感。阻挡在Gd2S2O:Tb层中创建的光学光子实际上将iEPID配置更改为dEPID配置,从而为可针对成像和剂量优化进行优化的系统展示了巨大的潜力。

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