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EPID‐based dosimetry to verify IMRT planar dose distribution for the aS1200 EPID and FFF beams

机译:基于EPID的剂量学验证aS1200 EPID和FFF光束的IMRT平面剂量分布

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摘要

We proposed to perform a basic dosimetry commissioning on a new imager system, the Varian aS1200 electronic portal imaging device (EPID) and TrueBeam 2.0 linear accelerator for flattened (FF) and flattening filter‐free (FFF) beams, then to develop an image‐based quality assurance (QA) model for verification of the system delivery accuracy for intensity‐modulated radiation therapy (IMRT) treatments. For dosimetry testing, linearity of dose response with MU, imager lag, and effectiveness of backscatter shielding were investigated. Then, an image‐based model was developed to convert images to planar dose onto a virtual water phantom. The model parameters were identified using energy fluence of the Acuros treatment planning system (TPS) and, reference dose profiles and output factors measured at depths of 5, 10, 15, and 20 cm in water phantom for square fields. To validate the model, its calculated dose was compared to measured dose from MapCHECK 2 diode arrays for 36 IMRT fields at 10 cm depth delivered with 6X, 6XFFF, 10X, and 10XFFF energies. An in‐house gamma function was used to compare planar doses pixel‐by‐pixel. Finally, the method was applied to the same IMRT fields to verify their pretreatment delivery dose compared with Eclipse TPS dose. For the EPID commissioning, dose linearity was within 0.4% above 5 MU and  ∼ 1% above 2 MU, measured lag was smaller than the previous EPIDs, and profile symmetry was improved. The model was validated with mean gamma pass rates (standard deviation) of 99.0% (0.4%), 99.5% (0.6%), 99.3% (0.4%), and 98.0% (0.8%) at 3%/3 mm for respectively 6X, 6XFFF, 10X, and 10XFFF beams. Using the same comparison criteria, the beam deliveries were verified with mean pass rates of 100% (0.0%), 99.6% (0.3%), 99.9% (0.1%), and 98.7% (1.4%). Improvements were observed in dosimetric response of the aS1200 imager compared to previous EPID models, and the model was successfully developed for the new system and delivery energies of 6 and 10 MV, FF, and FFF modes.PACS number(s): 87.53.Oq, 87.53.Xd
机译:我们建议在新的成像仪系统,用于平坦(FF)和平坦化无滤光片(FFF)光束的Varian aS1200电子门禁成像设备(EPID)和TrueBeam 2.0线性加速器上进行基本剂量学调试,然后开发图像-基于质量保证(QA)的模型,用于验证强度调制放射疗法(IMRT)治疗的系统交付准确性。对于剂量学测试,研究了剂量响应与MU的线性关系,成像器滞后以及反向散射屏蔽的有效性。然后,开发了基于图像的模型将图像转换为平面剂量到虚拟水体模上。使用Acuros治疗计划系统(TPS)的能量通量确定模型参数,并在方形模型的水模型中以5、10、15和20 cm的深度测量参考剂量曲线和输出因子。为了验证该模型,将其计算剂量与MapCHECK 2二极管阵列在10 cm深度处以6X,6XFFF,10X和10XFFF能量输送的36个IMRT场的测量剂量进行了比较。内部伽马函数用于逐像素比较平面剂量。最后,将该方法应用于相同的IMRT领域,以验证其与Eclipse TPS剂量相比的预处理递送剂量。对于EPID调试,剂量线性高于5 MU在0.4%以内,高于2 MU≥1%,测得的滞后时间小于以前的EPID,并且轮廓对称性得到改善。分别以3%/ 3 mm的平均伽玛通过率(标准偏差)分别为99.0%(0.4%),99.5%(0.6%),99.3%(0.4%)和98.0%(0.8%)验证了该模型6X,6XFFF,10X和10XFFF光束。使用相同的比较标准,以100%(0.0%),99.6%(0.3%),99.9%(0.1%)和98.7%(1.4%)的平均通过率验证光束的传输。与以前的EPID模型相比,aS1200成像仪的剂量响应得到了改善,该模型已成功开发用于新系统以及6和10 MV,FF和FFF模式的输送能量.PACS数:87.53。 ,87.53.Xd

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