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Leaf transmission reduction using moving jaws for dynamic MLC IMRT.

机译:使用动态MLC IMRT的移动钳口减少叶片传播。

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The aim of this work is to investigate to what extent it is possible to use the secondary collimator jaws to reduce the transmitted radiation through the multileaf collimator (MLC) during an intensity modulated radiation therapy (IMRT). A method is developed and introduced where the jaws follow the open window of the MLC dynamically (dJAW method). With the aid of three academic cases (Closed MLC, Sliding-gap, and Chair) and two clinical cases (prostate and head and neck) the feasibility of the dJAW method and the influence of this method on the applied dose distributions are investigated. For this purpose the treatment planning system Eclipse and the Research-Toolbox were used as well as measurements within a solid water phantom were performed. The transmitted radiation through the closed MLC leads to an inhomogeneous dose distribution. In this case, the measured dose within a plane perpendicular to the central axis differs up to 40% (referring to the maximum dose within this plane) for 6 and 15 MV. The calculated dose with Eclipse is clearly more homogeneous. For the Sliding-gap case this difference is still up to 9%. Among other things, these differences depend on the depth of the measurement within the solid water phantom and on the application method. In the Chair case, the dose in regions where no dose is desired is locally reduced by up to 50% using the dJAW method instead of the conventional method. The dose inside the chair-shaped region decreased up to 4% if the same number of monitor units (MU) as for the conventional method was applied. The undesired dose in the volume body minus the planning target volume in the clinical cases prostate and head and neck decreased up to 1.8% and 1.5%, while the number of the applied MU increased up to 3.1% and 2.8%, respectively. The new dJAW method has the potential to enhance the optimization of the conventional IMRT to a further step.
机译:这项工作的目的是研究在强度调制放射治疗(IMRT)期间,使用二级准直仪钳口以减少通过多叶准直仪(MLC)传输的辐射的可能性。开发并介绍了一种方法,其中钳口动态地跟随MLC的打开的窗口(dJAW方法)。借助3个学术案例(闭合MLC,滑动间隙和椅子)和2个临床案例(前列腺以及头部和颈部),研究了dJAW方法的可行性以及该方法对应用剂量分布的影响。为此,使用了治疗计划系统Eclipse和Research-Toolbox以及进行了固体水体模内的测量。通过封闭的MLC传输的辐射导致剂量分布不均匀。在这种情况下,对于6和15 MV,在垂直于中心轴的平面内测得的剂量相差40%(是指该平面内的最大剂量)。用Eclipse计算的剂量显然更均匀。对于滑动间隙情况,此差异仍高达9%。这些差异尤其取决于固体水体模内的测量深度和施加方法。在主席的情况下,使用dJAW方法而不是传统方法将不需要剂量的区域中的剂量局部降低多达50%。如果使用与常规方法相同数量的监控器(MU),则椅子形区域内的剂量最多减少4%。在临床情况下,前列腺和头部和颈部的体积体中不希望的剂量减去计划目标体积减少了多达1.8%和1.5%,而MU的应用数量分别增加了多达3.1%和2.8%。新的dJAW方法有可能将常规IMRT的优化进一步提高。

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