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Experimental investigation of a moving averaging algorithm for motion perpendicular to the leaf travel direction in dynamic MLC target tracking.

机译:动态MLC目标跟踪中垂直于叶片行进方向运动的移动平均算法的实验研究。

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PURPOSE: In dynamic multileaf collimator (MLC) motion tracking with complex intensity-modulated radiation therapy (IMRT) fields, target motion perpendicular to the MLC leaf travel direction can cause beam holds, which increase beam delivery time by up to a factor of 4. As a means to balance delivery efficiency and accuracy, a moving average algorithm was incorporated into a dynamic MLC motion tracking system (i.e., moving average tracking) to account for target motion perpendicular to the MLC leaf travel direction. The experimental investigation of the moving average algorithm compared with real-time tracking and no compensation beam delivery is described. METHODS: The properties of the moving average algorithm were measured and compared with those of real-time tracking (dynamic MLC motion tracking accounting for both target motion parallel and perpendicular to the leaf travel direction) and no compensation beam delivery. The algorithm was investigated using a synthetic motion trace with a baseline drift and four patient-measured 3D tumor motion traces representing regular and irregular motions with varying baseline drifts. Each motion trace was reproduced by a moving platform. The delivery efficiency, geometric accuracy, and dosimetric accuracy were evaluated for conformal, step-and-shoot IMRT, and dynamic sliding window IMRT treatment plans using the synthetic and patient motion traces. The dosimetric accuracy was quantified via a tgamma-test with a 3%/3 mm criterion. RESULTS: The delivery efficiency ranged from 89 to 100% for moving average tracking, 26%-100% for real-time tracking, and 100% (by definition) for no compensation. The root-mean-square geometric error ranged from 3.2 to 4.0 mm for moving average tracking, 0.7-1.1 mm for real-time tracking, and 3.7-7.2 mm for no compensation. The percentage of dosimetric points failing the gamma-test ranged from 4 to 30% for moving average tracking, 0%-23% for real-time tracking, and 10%-47% for no compensation. CONCLUSIONS: The delivery efficiency of moving average tracking was up to four times higher than that of real-time tracking and approached the efficiency of no compensation for all cases. The geometric accuracy and dosimetric accuracy of the moving average algorithm was between real-time tracking and no compensation, approximately half the percentage of dosimetric points failing the gamma-test compared with no compensation.
机译:目的:在具有复杂强度调制放射治疗(IMRT)场的动态多叶准直仪(MLC)运动跟踪中,垂直于MLC叶片行进方向的目标运动会引起光束保持,这将光束传送时间增加了多达4倍。作为平衡传递效率和准确性的一种手段,将移动平均算法合并到动态MLC运动跟踪系统(即移动平均跟踪)中,以解决垂直于MLC叶片行进方向的目标运动。描述了与实时跟踪相比没有移动补偿光束的移动平均算法的实验研究。方法:测量了移动平均算法的属性,并将其与实时跟踪(动态MLC运动跟踪考虑了平行和垂直于叶片行进方向的目标运动)的性能进行了比较,并且没有补偿光束的传递。使用具有基线漂移的合成运动轨迹和代表基线漂移不同的规则和不规则运动的四个患者测量的3D肿瘤运动轨迹对算法进行了研究。每个运动轨迹均由移动平台复制。使用合成运动轨迹和患者运动轨迹,评估了保形,分步式IMRT和动态滑动窗IMRT治疗计划的输送效率,几何精度和剂量学精度。剂量精确度通过tgamma试验以3%/ 3 mm的标准进行定量。结果:移动平均跟踪的交付效率范围为89到100%,实时跟踪的交付效率为26%-100%,无补偿的交付效率为100%(按定义)。均方根几何误差范围为移动平均值跟踪的3.2到4.0 mm,实时跟踪的0.7-1.1 mm和无补偿的3.7-7.2 mm。未通过伽玛测试的剂量点百分比范围为:移动平均跟踪为4%到30%,实时跟踪为0%-23%,无补偿为10%-47%。结论:移动平均跟踪的交付效率是实时跟踪的交付效率的四倍,并且在所有情况下都达到了无补偿的效率。移动平均算法的几何精度和剂量精度在实时跟踪和无补偿之间,与无补偿相比,伽玛测试失败的剂量点的百分比约为一半。

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