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Absolute dosimetry in a d(14 MeV) + Be fast neutron beam.

机译:d(14 MeV)+是快中子束中的绝对剂量。

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Since 1978, the Universitatsklinikum in Essen operates a d(14 MeV) + Be fast neutron beam for patient treatment. Dosimetric studies were performed in a rectangular 40 x 40 mm2 neutron/photon field using a transportable water calorimeter, which had been developed at the Physikalisch-Technische Bundesanstalt. The water calorimeter allowed small dosimeters to be directly calibrated in units of absorbed dose-to-water in a cylindrical phantom of 50 mm in diameter. Also, the twin detector method was applied in order to determine the photon and the neutron dose separately. By making use of a calibrated ionization chamber, the absorbed dose-to-water calibration in the cylindrical water phantom was transferred to a water phantom, a cube 300 mm on a side. Experiments and Monte Carlo calculations covering the neutron producing target, the collimator and the influence of the water calorimeter on the spectral neutron fluence at the measurement position allow the relative uncertainty of the absorbed dose-to-water determination to be reduced to 2.6% (1 SD). This direct absorbed dose-to-water determination by calorimetry has shown that the treatment planning system underestimates the physical dose to tissue by 9%. For clinical purposes, the statement of the prescribed dose had to be increased by 9% in order that the absolute absorbed dose remains constant and that the same biological endpoints are reached.
机译:自1978年以来,埃森大学(Universitatsklinikum)一直使用d(14 MeV)+ Be快速中子束治疗患者。剂量学研究是使用Physikalisch-Technische Bundesanstalt开发的便携式水量热计在40 x 40 mm2的矩形中子/光子场中进行的。水热量计允许以直径为50 mm的圆柱体模以吸收的剂量对水的单位直接校准小剂量计。同样,采用双探测器方法来分别确定光子和中子剂量。通过使用经过校准的电离室,将圆柱状水模中吸收的剂量对水的校准值转移到水模中,水模在侧面为300毫米。涵盖中子产生目标,准直仪和水热计对测量位置处的光谱中子注量的影响的实验和蒙特卡洛计算使吸收的剂量-水测定的相对不确定度降低到2.6%(1 SD)。通过量热法的这种直接吸收的剂量对水的测定表明,治疗计划系统低估了组织的物理剂量9%。出于临床目的,必须将规定剂量的说明增加9%,以使绝对吸收剂量保持恒定并达到相同的生物学终点。

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