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Judgment analysis of prioritization decisions within a dialysis program in one United Kingdom region.

机译:在一个英国地区的透析程序中对优先级决策的判断分析。

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BACKGROUND: Some previous research on rationed clinical services has confused the conceptual differences underpinning prioritization decisions on the one hand and assessments of individual need on the other. The balance of the clinical and nonclinical drivers of these decisions can be different. Our objective was to study the basis and extent of variation among nephrologists in one NHS region in their views concerning prioritization for dialysis. DESIGN AND METHODS: In a clinical judgment analysis, multiple regression analysis was used to express the impact of clinical and nonclinical cues on nephrologists' decisions to offer dialysis and attribute priority to 50 "paper patients." Cues were selected for the decision-making models using stepwise (backward) elimination of variables. Further "policy" models for priority were derived by forcing in the doctors' views about the capacity of dialysis to extend life expectancy or improve its quality. RESULTS: Comparison of "propensity to offer" and "prioritization" decision models showed a modest degree of correspondence. Among the nonrenal cues, the patient's mental state made the single greatest contribution to the priority decision models (mean contribution to R2 = 12.1, with temporary or permanent confusional states in patients changing the priority [1-50] by an average of 15 rank places). Although patient age significantly influenced the decision models of half of the doctors, the beta-coefficients were very modest, suggesting a change in rank order of no more than one place. There was a significant improvement in the overall explained variance (R2) of the models when varying perceptions of the capacity of dialysis to improve the quality or extend the duration of the patient's life were forced into the model. Although, in general, temporary or permanent confusion in the patient down-graded the priority for dialysis by between 10 and 20 places, this tendency was largely unchanged when the doctors' perceptions of benefit were forced into the priority model. Among renal cues, the presence of uremic symptoms had the greatest impact on priority (mean contribution to R2 = 49.1, mean beta-coefficient -17.1), whereas the presence of other comorbid disease had relatively little effect. CONCLUSIONS: When forced to rank patients, the nonrenal factor that had the most significant bearing on perceived priority for dialysis was the patient's mental state. However, the impact of the patient's mental state on priority did not appear to be driven by its influence on the doctors' perceptions of how dialysis might improve quality of life.
机译:背景:关于定量临床服务的一些先前研究混淆了概念上的差异,一方面支持优先级决策,另一方面评估个人需求。这些决定的临床和非临床驱动因素之间的平衡可能有所不同。我们的目标是研究一个NHS区域中的肾脏科医生在透析优先次序方面的基础和程度。设计与方法:在临床判断分析中,使用了多元回归分析来表达临床和非临床线索对肾脏科医生决定进行透析的影响,并为50名“纸质患者”提供了优先权。使用逐步(向后)消除变量为决策模型选择提示。通过迫使医生对透析能力延长预期寿命或改善其质量的观点得出进一步的“优先”政策模型。结果:“提供偏好”和“优先排序”决策模型的比较显示出适度的对应性。在非肾线索中,患者的精神状态对优先级决策模型的贡献最大(对R2的平均贡献= 12.1,患者的暂时性或永久性困惑状态将优先级[1-50]改变了15个等级)。尽管患者的年龄显着影响了一半医生的决策模型,但是β系数非常适中,表明排名变化不超过一位。当将对提高透析质量以提高质量或延长患者生命持续时间的透析能力的不同看法强加到模型中时,模型的总体解释方差(R2)有了显着改善。尽管通常情况下,患者的暂时性或永久性混乱将透析的优先级降低了10到20个等级,但是当医生的受益观念被迫纳入优先级模型时,这种趋势在很大程度上没有改变。在肾线索中,尿毒症症状的存在对优先级的影响最大(对R2的平均贡献= 49.1,平均β系数-17.1),而其他合并症的影响相对较小。结论:当被迫对患者进行排名时,与透析优先级密切相关的非肾脏因素是患者的精神状态。然而,患者的精神状态对优先级的影响似乎并不是由其对医生对透析如何改善生活质量的看法的影响所驱动。

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