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Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research.

机译:行政和临床数据中用于心力衰竭和合并症编码的比较,用于结果研究。

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摘要

BACKGROUND: Despite the potential usefulness of administrative databases for evaluating outcomes, coding of heart failure and associated comorbidities have not been definitively compared with clinical data. OBJECTIVE: To compare the predictive value of heart failure diagnoses and secondary conditions identified in a large administrative database with chart-based records. METHODS: The authors studied 1808 patient records sampled from 14 acute care hospitals and compared clinically recorded data with administrative records from the Canadian Institute for Health Information. The impact of comorbidity coding in the administrative data set according to the Charlson classification was examined in models of 30-day mortality. RESULTS: The positive predictive value (PPV) of a primary diagnosis ICD-9 428 was 94.3% using the Framingham criteria and 88.6% using criteria previously validated with pulmonary capillary wedge pressure. There was reduced prevalence of secondary comorbid conditions in administrative datain comparison with clinical chart data. The specificities and PPVegative predictive values of administratively identified index comorbidities were high. The sensitivities of index comorbidities were low, but were enhanced by examination of hospitalizations within 1 year prior to the index heart failure admission. Using information from prior hospitalizations modestly enhanced 30-day mortality model performance; however, the odds ratio point estimates of the index and enhanced administrative data sets were consistent with the clinical model. CONCLUSION: The ICD-9 428 primary diagnosis is highly predictive of heart failure using clinical criteria. Examination of hospitalization data up to 1 year prior to the index admission improves comorbidity detection and may provide enhancements to future studies of heart failure mortality.
机译:背景:尽管行政数据库对评估结局具有潜在的实用性,但心力衰竭和相关合并症的编码尚未与临床数据进行明确比较。目的:比较大型行政数据库中基于图表的记录所确定的心力衰竭诊断和继发状况的预测价值。方法:作者研究了从14家急诊医院采样的1808例患者记录,并将临床记录的数据与加拿大卫生信息研究所的行政记录进行了比较。在30天死亡率模型中检查了根据Charlson分类在管理数据集中的合并症编码的影响。结果:使用弗雷明汉标准,初步诊断ICD-9 428的阳性预测值(PPV)为94.3%,而使用先前经肺毛细血管楔压验证的标准,则为88.6%。与临床图表数据相比,行政数据中次要合并症的患病率有所降低。行政上确定的指数合并症的特异性和PPV /阴性预测值较高。指数合并症的敏感性较低,但在指数性心力衰竭入院前一年内通过住院检查得到了增强。使用先前住院的信息适度提高了30天死亡率模型的性能;但是,该指数和增强型管理数据集的优势比估计值与临床模型一致。结论:根据临床标准,ICD-9 428的初步诊断可高度预测心力衰竭。入院前1年以内的住院数据的检查可改善合并症的检测,并可能为心力衰竭死亡率的未来研究提供进一步的支持。

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