Preparation of Highly Cross-Linked,Monodisperse Poly(methyl methacrylate)Microspheres by Dispersion Polymerization;Part II.Semi-continuous Processes

摘要

In our previous publication,the problem of particle deformation and coagulation at the nucleation stage in the presence of cross-linker was intensely studied by seeded batch dispersion polymerization of methyl methacrylate (MMA).In the present work,highly cross-linked,monodisperse PMMA particles were prepared under various reaction conditions by seeded semi-continuous process.Monodisperse,6.5 mu m-diameter PMMA particles containing up to 8 wt% of DVB or EGDMA were successfully made by seeded semi-continuous process and multi-semi-continuous addition process,respectively.Therefore,this study shows that seeded semi-continuous process is more effective and efficient to prepare highly cross-linked,monodisperse particles than non-seeded and seeded batch processes.