New Possibilities of the Acetosulfation of Cellulose

摘要

Regioselectively substituted cellulose sulfates in C2/3-, C2/6-, orC6-position of the anhydroglucose unit are accessible by certain synthesis routes.Thereby, products with different properties and various application areas are resulted.Important characteristics of cellulose sulfates regarding their applications aresolubility (e.g. in water), rheological behavior, different interaction with low or highmolecular cations, thermo reversible gel formation, enzymatic degradability, antic-oagulant and antiviral activity. In C6-position substituted cellulose sulfates can besynthesized in principle by acetosulfation. The acetosulfation is a quasi-homogeneoussynthesis proceeding under gradually dissolution of the cellulose by using differentreactivity of the primary and secondary OH-groups as soon as converting celluloseacetate sulfates. After precipitation of the polymer the acetyl groups are cleaved inalkaline solution. The focus of our study was firstly the investigation of the acetosulfa-tion in different polar aprotic solvents by various sulfating and acetylating agents. Ingeneral it should be investigated if C6 substituted cellulose sulfates can be obtained byacetosulfation with different solvents and agents. The products were characterized by13C-NMR and Raman spectroscopy.