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Celiac Disease and Dermatologic Manifestations: Many Skin Clue to Unfold Gluten-Sensitive Enteropathy

机译:乳糜泻和皮肤病表现:许多皮肤线索显示出麸质敏感性肠病

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摘要

Cutaneous manifestations of intestinal diseases are increasingly reported both in the adult and in the children, and this association cannot longer be considered a simple random. Besides the well-known association between celiac disease (CD) and dermatitis herpetiformis (DH), considered as the cutaneous manifestation of gluten-dependent enteropathy, is more frequently reported also the association with other mucocutaneous diseases. Among these there are both autoimmune, allergic, and inflammatory diseases, but also a more heterogeneous group called miscellaneous. The knowledge about pathogenic, epidemiological, clinical, and diagnostic aspects of CD is increasing in recent years as well as those about DH, but some aspects still remain to be defined, in particular the possible pathogenetic mechanisms involved in the association between both CD and DH and CD and other immunological skin diseases. The aim of this paper is to describe the skin diseases frequently associated with CD, distinguishing them from those which have a relationship probably just coincidental.
机译:成人和儿童中肠道疾病的皮肤表现越来越多,而且这种关联不再被认为是简单的随机现象。除了众所周知的腹腔疾病(CD)和疱疹样皮炎(DH)之间的关联(被认为是面筋依赖性肠病的皮肤表现)外,还经常报道与其他粘膜皮肤疾病的关联。其中既有自身免疫性疾病,变应性疾病和炎性疾病,也有杂种性更强的一组。近年来,关于CD的致病,流行病学,临床和诊断方面的知识以及关于DH的知识都在增加,但是仍有一些方面尚待确定,特别是CD和DH之间关联所涉及的可能的致病机制。以及CD和其他免疫性皮肤病。本文的目的是描述经常与CD相关的皮肤疾病,以区别于那些与CD相关的皮肤疾病。

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