Differential clinical presentations of epstein-barr virus infection and a brief literature review

摘要

Epstein-Barr virus (EBV), a member of the gamma herpes virus family, is a common virus worldwide that is the causative agent of infectious mononu-cleosis syndrome. Although EBV infections are generally asymptomatic during childhood, symptomatic presentation is more common with increasing age. Approximately 80%-90% of patients with EBV infection remain undi-agnosed as the asymptomatic increase in liver function tests is the only manifestation in the majority of the cases (Crum, 2006; Schooley, 2000). Cholestatic hepatitis, liver failure (due to acute or chronic disease), autoimmune hepatitis, hepatocellular carcinoma, and splenic rupture have all been reported in association with EBV infection. In this article, several different clinical pictures of EBV infection are reported, along with a brief literature review.