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首页> 外文期刊>Forensic science international >Surface granularity as a discriminating feature of illicit tablets.
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Surface granularity as a discriminating feature of illicit tablets.

机译:表面粒度是非法片剂的一个区别特征。

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In this paper we propose an innovative methodology for automated profiling of illicit tablets by their surface granularity; a feature previously unexamined for this purpose. We make use of the tiny inconsistencies at the tablet surface, referred to as speckles, to generate a quantitative granularity profile of tablets. Euclidian distance is used as a measurement of (dis)similarity between granularity profiles. The frequency of observed distances is then modelled by kernel density estimation in order to generalize the observations and to calculate likelihood ratios (LRs). The resulting LRs are used to evaluate the potential of granularity profiles to differentiate between same-batch and different-batches tablets. Furthermore, we use the LRs as a similarity metric to refine database queries. We are able to derive reliable LRs within a scope that represent the true evidential value of the granularity feature. These metrics are used to refine candidate hit-lists form a database containing physical features of illicit tablets. We observe improved or identical ranking of candidate tablets in 87.5% of cases when granularity is considered.
机译:在本文中,我们提出了一种创新方法,可通过非法片剂的表面粒度对其进行自动轮廓分析。以前未经检查的功能。我们利用药片表面的微小不一致性(称为斑点)来产生药片的定量粒度分布。欧几里得距离用作粒度分布图之间(非)相似性的度量。然后通过核密度估计对观察到的距离的频率进行建模,以概括观察结果并计算似然比(LRs)。所得的LR用于评估粒度分布图的潜力,以区分相同批次和不同批次的片剂。此外,我们使用LR作为相似性指标来细化数据库查询。我们能够在表示粒度特征的真实证据值的范围内得出可靠的LR。这些指标用于优化候选列表,形成包含非法药片物理特征的数据库。在考虑粒度的情况下,我们观察到87.5%的情况下候选片剂的排名得到改善或相同。

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