COMPARISON OF ACID-BASE PARAMETERS IN VENOUS BLOOD OF PIGS BEFORE AND AFTER SHORT-TERM SURGICAL ANAESTHESIA

摘要

The aim of this study was to analyse the influence of shortterm injection anaesthesia (azaperon — Stresnil inj., Janssen Pharmaceutica; diazepam — Apaurin inj., Krka; ketamine — Ket-amidor 10% inj., Richter Pharma AG) on the pH and concentration ofblood gases in the venous blood of pigs. The parameters of; acid-base profile — pH, pCO_2, pO_2, HCO_3, standard bicarbonate SBi, base excess BE, and oxygen saturation, were monitored in two different surgical procedures. Five boars (crossbreed Large White and Landrace, mean body weight 30.4 kg, 3 months old) had surgery outside of the abdominal cavity — castration + inguinal hernia repair. Four gilts (crossbreed Large White and Landrace, mean body weight 78.75 kg, 5 months old) had surgery in the abdominal cavity — ovariectomy. Blood samples were taken before anaesthesia (0 sampling), and 15 minutes (castration) and 120 minutes (ovariectomy) respectively, after the administration of ketamine (1st sampling). The statistical comparison of acid-baseparameters before and after castration showed significant increases of partial pressure of (4.80 to 9.20 kPa; P<0.05) and saturation of Oj (63.80 to 92.20%; P<0.05). On the other hand, the statistical comparison of samplings before and after ovariectomies showed no significant differences. The comparison between surgical procedures showed significantly lower values of pH (7.32; P<0.01), HCO_3 (23.00mmoL~(-1); P<0.05), SBi (21.25mmoL~(-1); P<0.05) and BE (-3mmol. 1'; P<0.05) after ovariectomies. The obtainedresults confirm the differences of blood parameters depending on the duration of the surgery.