Long term follow-up after a single intravitreal ranibizumab injection for choroidal neovascularisation secondary to optic nerve head drusen in a 5-year-old child

摘要

Dear Editor, A 5-year-old boy presented with a 10-day history of blurred vision in his left eye. Visual acuity (VA) was 20/60. Fundu-scopy, ultrasonography, and Fluorescein/ICG angiographies (Fig. 1) associated with optical coherence tomography (OCT) (Fig. 2a,b) revealed a classic choroidal neovascular (CNV) membrane complicating buried optic nerve head drusen (ONHD). After an informed consent was obtained, the patient underwent an intravitreal ranibizumab injection (0.5 mg) under general anaesthesia. VA improved to 20/30 at month 1, 20/25 at month 2 and remained stable over a 12-month follow-up period. No recurrence of the neovascular activity was observed (Fig. 2c,d).