Perioral dermatitis in a patient with myasthenia gravis following systemic corticosteroid treatment.

摘要

Sir, Perioral dermatitis is a common dermatosis presenting as a persistent erythematous eruption composed of tiny papules and papulopustules distributed symmetrically around the mouth, and over the chin. A narrow zone of sparing around the vermilion border of the lips is a pathognomonic feature. Additional lesions may arise on the nasolabial folds, glabella, periocular skin and eyelids. Facial flushing and comedones are notably absent. Classically, perioral dermatitis develops secondary to the use of topical corticosteroids or facial cosmetics.' Young women (age 16-45 years) are most often affected, although cases involving children and men have been reported. Treatment requires cessation of the offending agent with or without the addition of antibiotics such as tetracydine or erythromycin. Without adequate treatment, the disease tends to run a persistent and fluctuating course. While perioral dermatitis has been closely associated with topical corticosteroid use, the emergence of this condition in patients taking systemic corticosteroids has rarely been reported in the literature.