Classical swine fever virus: clinical, virological, serological and hematological findings after infection of domestic pigs and wild boars with the field isolate 'Spante' originating from wild boar.

摘要

The virulence of a classical swine fever virus (CSFV) field isolate originating from wild boar was investigated in domestic pigs and wild boar. Three weaner pigs and 2 wild boars (yearlings) were inoculated intranasally with the isolate "Spante". Clinical, virological, haematological and serological findings were recorded for 31 days after infection. Infected piglets were put in contact with sentinel pigs 1 day after infection. Neither pigs nor wild boars showed clinical signs of CSF during the observation period. Two infected weaner pigs became transiently viraemic, transmitted CSFV in nasal secretions, showed a slight leukopenia and they were serologically positive. Contact infection resulted in a viraemia in 2 sentinel piglets on day 30. Only one contact animal developed antibodies. None of wild boars became viraemic, excreted CSFV in nasal secretions or developed antibodies. It is concluded that "Spante" isolate has low virulence.