Mannich type reactions of chlorophosphites, phosphoramides and aldehydes (ketones) under solvent-free and catalyst-free conditions - synthesis of N-phosphoramino alpha-aminophosphonates

摘要

A convenient and rapid method was developed for the synthesis of various N-phosphoramino alpha-aminoalkylphosphonates through Mannich type reactions under catalyst- and solvent-free conditions with excellent yields.