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首页> 外文期刊>British Journal of Dermatology >Increased expression of CXCR3 and its ligands in patients with vitiligo and CXCL10 as a potential clinical marker for vitiligo
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Increased expression of CXCR3 and its ligands in patients with vitiligo and CXCL10 as a potential clinical marker for vitiligo

机译:CXCR3及其配体在白癜风患者中的表达增加,CXCL10作为白癜风的潜在临床标志物

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摘要

Background Vitiligo is a skin disorder characterized by loss of melanocytes from the epidermis. A recent study reported that CXCL10 is critical for the progression and maintenance of depigmentation in a mouse model of vitiligo, but there is very limited clinical data regarding this issue and little is known about the dynamic changes or correlations with disease severity of these chemokines throughout the disease course.
机译:背景白癜风是一种皮肤疾病,其特征是表皮中黑色素细胞的丢失。最近的一项研究报道,CXCL10对于白癜风小鼠模型中色素沉着的进展和维持至关重要,但是关于此问题的临床数据非常有限,并且关于这些趋化因子在整个疾病过程中的动态变化或与疾病严重性的关系知之甚少病程。

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