HAPLOT: a graphical comparison of haplotype blocks, tagSNP sets and SNP variation for multiple populations

摘要

Understanding of human variation relevant to association studies can benefit from population comparison, especially comparing populations in the same geographical region. Variations in linkage disequilibrium patterns, in tagSNP sets, and in SNP heterozygosities among populations can be used to infer the evolutionary pattern. We present here a Win32 system based Perl/Tk application for visual comparisons of these variations in different populations.