Chemoselective Oxidation of Sulfides Promoted by a Tightly Convoluted Polypyridinium Phosphotungstate Catalyst with H2O2'

摘要

Sulfones have generated considerable interest due to their presence in a number of biologically active compounds and also to their utility in organic synthesis.1 Sulfide oxidation is one of the standard approaches to sulfones, where a stoichiometric or larger amount of hazardous oxidants such as KMnO4, MCPBA, and MMPP is often required. If sulfides could be efficiently oxidized with hydrogen peroxide by using a recyclable catalyst, the catalytic oxidation system would provide a viable, safe, clean, and environmentally benign alternative to the conventional stoichiometric oxidations. While there has been no lack of pioneering work on sulfide oxidation with aq. H2O2 promoted by a homogeneous catalyst, the heterogeneous-switching of the catalytic oxidation to meet green chemical requirements still remains a major challenge.