A review of long-term effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol and triglyceride.

摘要

Low sodium diets have been a major hypertension prevention and treatment theme. Evidence supporting interventions of reduced sodium intake as a generalised hypertension prophylaxis initiative remains ambiguous.Although a diet high in sodium has been associated with development of hypertension and cardiovascular disease, population study data have been conflicting and showed direct harmful effects in patients with heart failure and diabetes. Sodium intake has been shown to effect the renin-angiotensin-aldosterone system, catecholamines and serum lipids that are surrogate markers of cardiovascular disease, thus questioning the generalised advisability of reduced sodium intake recommendations.