Association between recent stressful life events and prevalence of depression, anxiety and PTSD differs according to exposure to childhood adversity.

摘要

QUESTION Question: Does the relationship between recent past-year stressful life events and prevalence of psychiatric disorder vary according to exposure to childhood adversity (CA)? Population: 34 653 civilian, non-institutionalised adults aged 18 years or older. Participants were taking part in the second wave of the National Epidemiologic Study of Alcohol and Related Conditions. Setting: General population, USA; 2004-2005. Assessment: The Alcohol Use Disorder and Associated Disabilities Interview Schedule - DSM-IV Version (AUDADIS-IV) was used to assess stressful life events and psychiatric diagnoses in the past 12 months. Experience of CA before the age of 17 was assessed retrospectively using various questionnaires, and included physical, emotional or sexual abuse; neglect or parental dysfunction (domestic violence, serious mental illness, criminality or substance abuse).