首页> 外文期刊>European journal of ophthalmology >Vitrectomy for treatment of a lamellar hole in a patient with exudative macular degeneration: the role of vitreous traction elimination.
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Vitrectomy for treatment of a lamellar hole in a patient with exudative macular degeneration: the role of vitreous traction elimination.

机译:玻璃体切除术治疗渗出性黄斑变性患者的片状孔:玻璃体牵引消除的作用。

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PURPOSE: Lamellar macular hole (LMH) represents a well-defined clinical entity with variable pathophysiologic mechanisms and a controversial therapeutic approach. The purpose of the present work is to present a patient with an epiretinal membrane (ERM)-associated LMH on the background of exudative age-related macular degeneration (AMD) that was successfully managed with pars plana vitrectomy. METHODS: Interventional case report. RESULTS: A 67-year-old man presented with progressive visual loss OS of 5 months' duration. He was diagnosed with an ERM-associated LMH with coexisting subretinal fluid arising by a neovascular membrane on the background of exudative AMD confirmed with fundus fluorescein angiography. He underwent a 3-port pars plana vitrectomy with ERM-internal limiting membrane peeling and gas tamponade (14% C3F8) for treatment of the LMH and ERM with a view to undergo anti-vascular endothelial growth factor treatment for the exudative AMD. Postoperative optical coherence tomography demonstrated complete closure of the LMH with simultaneous total subretinal fluid absorption that was maintained at the 2-month follow-up period. CONCLUSIONS: To our knowledge, this is the first report whereby pars plana vitrectomy in a patient with an ERM-associated LMH on the background of exudative AMD resulted in improvement of both clinical entities. The latter strengthens the role of vitreous traction elimination in exudative AMD and highlights the need for further research.
机译:目的:层状黄斑裂孔(LMH)代表一个定义明确的临床实体,具有可变的病理生理机制和有争议的治疗方法。本工作的目的是在渗出性年龄相关性黄斑变性(AMD)的背景下向患者介绍与视网膜前膜(ERM)相关的LMH,该患者已通过pars平板玻璃体切除术成功治疗。方法:介入病例报告。结果:一名67岁男子表现为持续5个月的进行性视力减退。在渗出性AMD的背景下,经眼底荧光血管造影证实,他被诊断出患有ERM相关LMH,并伴有新血管膜引起的视网膜下液共存。他进行了3孔pars玻璃体切除术,使用ERM内部限制膜剥离和气体填塞(14%C3F8)治疗LMH和ERM,以针对渗出性AMD进行抗血管内皮生长因子治疗。术后光学相干断层扫描显示LMH完全闭合,同时在2个月的随访期间维持了视网膜下总液体吸收。结论:据我们所知,这是第一份报道,在渗出性AMD的背景下,患有ERM相关LMH的患者进行平面玻璃体切除术可改善两个临床实体。后者加强了玻璃体牵引消除在渗出性AMD中的作用,并强调了进一步研究的必要性。

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