A 48-year-old woman was referred to our hospital for evaluation of a long-stalked gastric polypoid lesion, which was found incidentally during upper endoscopy screening. Her medical history was unremarkable, and she did not describe having any GI symptoms. The results of physical examination were unremarkable. EGD showed a 1.5-cm pol-ypoid lesion with an erythematous head (A) and a long pedicle (B). EUS revealed an anechoic lesion with multiple septae, located superficially to the muscularis mucosa (C). She underwent polypectomy by use of a detachable snare. Gross pathologic examination revealed multiple internal cystic portions that were seen on serial sections (D). Microscopic pathologic examination showed disruption of the muscularis mucosa (arrow) and invaginated cystic glands of varying sizes in the submucosa (E) compatible with gastritis cystica profunda.
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