EUS 2008 Working Group document: evaluation of EUS-guided vascular therapy

摘要

INTRODUCTION AND PROCEDURESGI bleeding is a common condition and results in approximately 400,000 hospitalizations annually in the United States. GI bleeding arises from a variety of etiologies and is associated with substantial morbidity and mortality, and health care cost.1'3 There are a number of well-established endoscopic techniques used to identify the bleeding source and to deliver safe and effective he-mostasis. Despite advances in imaging and angioembolic therapy of GI hemorrhage, rebleeding occurs in 15% to 20% of patients and results in substantive morbidity and mortality. Lesions refractory to initial therapy usually require repeated endoscopy and/or radiologically guided interventional therapy, or even surgical ligation or resection. As a result, more effective therapies are needed for primary control of bleeding and for managing rebleeding after failed standard interventions. This unmet need has driven the development of new technologies, such as endoscopic suturing and cryotherapy, to manage GI bleeding.